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烧伤
作者:管理员    发布于:2013-07-17 15:49:17    文字:【】【】【

美国鸸鹋协会与Timothy J. Harner 烧伤中心的主任John Griswold 博士于1995年第一季度合作,利用4-6个月的时间来分析鸸鹋油潜在的、有效的治疗烧伤作用,此项研究由位于得克萨斯州Lubbock的得州州立大学提供协助。
传统治疗烧伤是很痛苦的,而且伤口很难恢复。发炎、脱水以及过敏是临床治疗过程中的常见情况。目前所用的润滑药在渗透力、减少过敏和疼痛方面作用各种各样,需要在脂肪腺耗尽或丧失功能的烧伤创面使用适当的润滑油通过提供水分来辅助治疗。
炎症是治疗烧伤时出现的正常反应。炎症会导致伤疤组织的生成。每年约有近二百五十万人寻找药物治疗烧伤。在所有伤口恢复过程中使用润滑剂是很重要的。这就存在对鸸鹋油的巨大需求。
据美国鸸鹋协会1997年1月从Griswold的研究中称,他对本来需9个月才可以恢复的烧伤患者正在接受对比治疗。这种试验要求在同一患者伤口位于身体的完全隔离的、对称的两侧,用相同的方法治疗来比较使用鸸鹋油与其他药物的治疗效果。根据治疗结果的数据得到两个重要结论:
无论是治疗结果还是治疗过程中,都无一例外地显示使用鸸鹋油的效果要好。通过对三位双盲试验者伤口恢复过程中的照片的比较,使用鸸鹋油与其它药物在减少疤痕和炎症方面在统计学上具有一致的显著性差别。
在美国鸸鹋协会1998年3月18-21日的会议期间,出示了完整的研究结果。文章的标题是:《鸸鹋油在治疗烧伤中润滑和治疗作用的评价》,署名作者是Penturf博士,O’Banion 研究员和Griswold医学博士。
完整的摘要已提交给美国烧伤协会。鸸鹋油具有显著的抗炎症效果,在化妆品和治疗上已经使用。试验证明鸸鹋油在治疗烧伤中作为润滑剂、减少疤痕生成的作用。十位病人经过为期6个月的随机双盲试验,其身体两侧伤口使用鸸鹋油和其它舒缓润滑剂。根据临床观察,使用Vancouver伤疤评价方法进行伤口评估。并将各个临床结果拍照。治疗过程持续195-385天不等。病人为男性,年龄介于24-63岁之间。根据对每一个伤疤的评估,其色素沉着和柔韧性方面存在极显著差异(p<0.02),在伤口血管分布和伤口高度方面无显著差异(p=0.08)。记录了四人色素沉着状态的照片,伤口化脓和一般皮肤状况。根据照片对比,鸸鹋油治疗的伤口明显比其它药物治疗的伤口要好(p<0.02)。
使用统计学的F分布来分析不同方法得出的不同数据。初步研究表明鸸鹋油在治疗烧伤方面是很有效的,但需做进一步的研究以阐明鸸鹋油的治疗机理。既然研究结果已在专文上披露,此摘要可在研究中予以引用。
內文节录自 :Evaluation of Emu Oil In Lubrication and Treatment of Healed Burn Wounds, S O’ Banion, J. Griswold, Texas Tech University Health Sciences Center, Lubbock Texas; American Burn Association, March 18, M1998. Chicago, Illinois.


乳癌病人在放射治疗后使用鸸鹋油治疗烧伤案例(完文节录)
Radiation Burns Cancer Patient
by Myra Charleston
Editors' Note: We are withholding the name of this cancer patient at her request due to the nature of the photos in this article. Please note that "Mrs. X" is fair skinned and had a very adverse reaction to the radiation. Most radiation patients do not experience burns to this extent during radiation therapy. This article is very graphic intensive.
After finding a pea-sized lump in her breast, this 65-year-old Oregon lady went through a whirlwind of doctors’ visits and treatments. Her July surgery found a cancerous lump less than a centimeter across; but, fortunately; the 16 lymph nodes removed were cancer cell free. As a precaution, the surgeon recommended radiation therapy.
Starting in the latter part of September 2000, she received radiation therapy daily Monday through Friday for two weeks. “By the second week the breast was burned black – there was actually soot,” Mrs. X reported. “When I showered in the mornings, the shower pads were turned charcoal.” After having a week off from the radiation therapy, she returned for her second set of treatments. The technician did not like the way her skin was looking and asked the doctor on call to take a look at her. Despite the half dollar sized wound under her arm, swollen breast and the burned skin, he ordered the treatments to continue. On October 26th, a Thursday, she told the technician she would not be in for the final treatment in that set because she had an appointment with her surgeon. By this time the skin was raw under the breast and arm, with open wounds in several areas. Mrs. X was unable to sleep and in constant pain. When her doctor saw the wounds, he was horrified and ordered the treatments be discontinued. In the course of her visit, the surgeon recommended that she try emu oil for the burns. Earlier that same day her husband had received the same advice from a clerk at the local pharmacy. The following is a pictorial documentation of her wound care results with emu oil.
 This photograph was taken October 30, 2000,     prior to the use of emu oil. Notice how pale the skin normally is on the arm and above the breast. The top layer of skin is burned off - in the upper right of the photograph you can still see the charred remains of skin after Mrs. X has showered off the soot.
Unable to wear a bra because of the raw skin and in constant pain, the only way to achieve any comfort was to keep moist Telfa pads under the breast. For a more detailed view, and to see the charred areas a little better, click on the photo. This is a large photograph and will take some time to come up.
Also taken on October 30, 2000, this view of Mrs. X's left breast shows the incisions made during her July surgery, the huge burned areas and some of the "hot spots" that developed blisters which later burst and became open wounds.
The large open wound directly under her arm started out as a half dollar sized wound, and got worse when the doctor on call ordered a continuation of the radiation treatments. Mrs. X tells us that the breast was so swollen, it actually gained a cup size. The three "hot spots" in the lower part of the picture are outlined below.
Click on the picture to the left to view an enlargement detailing three "hot spots" in various stages of development. Pay special attention to the blister in the center. Click on the picture to the right to view an enlargement detailing the wound under the arm.
With her husbands' assistance, Mrs. X started using emu oil on her burns on November 3, 2000. Unable to touch the breast without pain, the creamy emu oil was initially applied to Mrs. X's breast by her husband using a tongue depressor (with her holding her breath as he went over some areas). Later applications were made by spreading emu oil on a Telfa Pad and then placing the pad on the burn area. This was done three or four times a day. The pictures below outline the treatment results.
The next three photographs detailing the wounds on the underside of the breast and on the area between the breast and waist were taken on November 7, 2000.
At the time these photographs were taken, Mr. X had been applying Emu oil as outlined above three or four times a day for four days to his wife's burns.
Note the charred, raw skin and deep wounds displayed same day, the camera angle is slightly different in each to better detail the skin damage. Click on the picture to the right to view a close up of the raw area between the breast and waist. The photo below left details the burn area underneath the breast.
Up to this point Mrs. X had been unable to sleep due to the agony. Anything touching the breast hurt. The areas where skin touched skin, such as under the arm or under the breast, were in constant pain. According to Mrs. X, "The second night after applying emu oil only 2 days, three or four treatments per day, I was able to get some well needed sleep."
By November 10, 2000, when these photos were taken, there had been marked improvement. According to Mrs. X, the emu oil seemed to help bring the "heat" out of the breast. Deep burn wounds healed from the inside out. Click on the photo to see a detailed enlargement.
Most of the raw, red areas shown in the October 30 photos were now pink new skin. Only the deepest wounds were still raw. The large raw area directly underneath the arm now has skin, although the charred rough areas are still visible. The large, sideways keyhole shaped red area is where the blister shown in the November 30th photographs has grown larger and burst. Note the red area on the underside of the breast, below the burst blister area.
The area with the three "hot spots" progressed. The large blister continued to grow until it finally ruptured, making a red, raw, sideways keyhole shape. Click on the picture to the left to see an enlargement of the wound. The smaller wound to the left is nearly healed, but because it was so deep is still a little bit raw.
These pictures were taken on November 15, 2000, 12 days after Mrs. X started using emu oil on her radiation burns.
The photo to the left was taken at an angle to show the underside of the breast, which is almost completely healed. The white scar is all that is left of the red area on the underside of the breast shown in the photo taken on November 10. The keyhole shaped wound has undergone significant healing, as shown in the enlargement below.
As you can see from the enlargement to the right, the "hot spot" area that progressed from a blister to become a red, raw, sideways keyhole shape has made considerable progress towards healing. Most of the area is now pink new skin, with some areas still scabbed over. The deep wound to its' left still has a slight pink discoloration, but is healed. The area to the right (see larger photo) is healed, but the skin is discolored.
The underside of the breast has been very slow to heal due to the moist environment.
This area remains discolored from the radiation burns, but is almost completely healed. New pink skin is evident with only a couple of "tender" spots left to heal on the underside of the breast. The area between the breast and the waist is completely healed.
The only evidence of the raw underarm wounds pictured in the October 30 photos are the scars outlining the radiation burn area and the brown skin discoloration where the deep wound was located. As you can see from this photo, the edges of the radiation burns are still very obvious, although no longer painful. "At this point I could rub it (the emu oil) on myself" she tells us.
It has now been two years since Mrs. X underwent cancer surgery and radiation therapy. She has had no recurrence of the cancer. Regarding emu oil, she tells us that she will never be without it in her home, though she hopes she never needs it for the same reason that she did originally. She tells us that "We were happy that the bottle of emu oil was a little on the creamy side." because it was easier to apply with the tongue depressor. "We tell everyone who asks how wonderful it is" says Mrs. X.

在现有乳癌病人在放射治疗后使用鸸鹋油治疗烧伤方面
在美国的Cancer Care Northwest已正式使用鸸鹋油治疗乳癌病人在放射治疗后的创伤. (见參考资料)

参考资料
1. Experimental Study to Determine the Anti-Arthritic Activity of New Emu Oil Formulation (EMMP)(1993)
By: Dr. Peter Ghosh at Royal North Shore Hospital of Sydney, Australia and Dr. Michael Whitehouse at University of Adelaide, Australia.
2. Fatty Acid Analysis of Emu Oil
By: Dr. Paul Smith, Dr. Margaret Craig-Schmidt, Amanda Brown at Auburn University.
3. Fatty Acid Composition: Comparative analysis of emu, ostrich and rhea oil.
By: Dr. Margaret Craig-Schmidt and K.R. William at Auburn University. (1996)
4. International Emu Oil Guidelines
By: The AEA Oil Standards Team, Lee D. Smith (Team Leader) (1997)
5. Emu Oil: Comedogenicity Testing
By: Department of Dermatology, at University of Texas Medical School, Houston.(1993)
6. Moisturizing and Cosmetic Properties of Emu Oil: A Double Blind Study
By: Dr. Alexander Zemtsov, Indiana University School of Medicine: Dr. Monica Gaddis, Ball Memorial Hospital; and Dr. Victor Montalvo-Lugo, Ball Memorial Hospital. (1994)
7. Composition of Emu Oil: The Micro View
By: Dr. Leigh Hopkins, AEA Oil Standards Team (Research Leader) (1997)
8. Emu Cream Assists Lidocaine: Local Anesthetic Absorption through Human Skin
By: Dr. William Code. (Presented at the 88th American Oil Chemists Society annual meeting, May 1997)
9. Emu Oil: A Source of Non-Toxic Transdermal Anti-Inflammatory Agents in Aboriginal Medicine (1997)
By: Dr. Michael Whitehouse and Athol Turner, Dept. Of Medicine, University of Queensland, Australia (Source: Inflammapharmacology, San Francisco, March 1997 conference proceedings).
10. Proliferative Activity of the Skin and Excelerated Hair Growth
Dr. Michael Holick, M.D, Ph.D., Professor of Medicine, Physiology, and Dermatology at Boston University School of Medicine

参考书目:
1. Commonwealth of Australia, Department of Health, Housing, and Community Services, Centificate of a pharmaceutical Product No.92/0980.
2. AUSTR 22759 in the Australian Register of Therapeutical Goods.
3. Singh J, Mabach HI. Topical Iontophoretic Drug Delivery in vivo Histminal Development, Devices, and Future Respectives. Dennatology 1993, 187,235,238.
4. Korting HC, Blechek P, Schaefer-Korting M, Wendel A. Topical lipsome drug to come: What the patent literature tells us. A review J Am Academy of Dermatology 1991,15:1068-1071.
5. Schaefer-Korting M, Korting HC, BraunFalco O. Liposome preparations; A Step forward in topical drug therapy for skin disease. A Review J Am Academy of Dermatology 1989, 21:1271-1275.
6. Wester RC, Maibach HI. Dermatopharmokinetics in clinical Dermatology. Semin Dermatol 1983, 2:81-84.

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